Tadalista 2.5 works by increasing blood flow to the penis. You can take Tadalista 2.5 with or without food. It needs to be taken just as your doctor has advised. One hour is the suggested waiting period before engaging in sexual activity. Although everyone's work takes a varied amount of time, it typically takes 30 to 60 minutes. For this drug to help you get an erection, you need to be sexually stimulated. However, you shouldn't use this drug if you don't have erectile dysfunction. The most common adverse effects of this medicine are headaches, lightheadedness, flushing, sore muscles, and impaired vision.